Language System

Hallucinations, Formal Thought Disorder & the Language System

The language dimension includes formal thought disorders such as incoherence, perplexity or alogia.

 

 

Auditory Verbal Hallucinations
No Effect of Transcranial Direct Current Stimulation of the Auditory Cortex on Auditory-Evoked Potentials
Kunzelmann et al., Front Neurosci 2018;12:880
DOI: 10.3389/fnins.2018.00880

Neurofeedback-Based Enhancement of Single Trial Auditory Evoked Potentials: Feasibility in Healthy Subjects
Rieger et al., Clin EEG Neurosci 2018;49:79–92
DOI: 10.1177/1550059417708935

Decreased NAA levels (MRS) in Broca's in non hallucinating schizophrenics compared to hallucinators
Homan et al., Neuroimage 2014;94:23–32
DOI: 10.1016/j.neuroimage.2014.03.009

Cerebral blood flow identifies responders to transcranial magnetic stimulation in auditory verbal hallucinations.
Homan et al., Transl Psychiatry 2012;2:e189
DOI: 10.1038/tp.2012.114

Reduced neuronal activity in language-related regions after transcranial magnetic stimulation therapy for auditory verbal hallucinations
Kindler et al., Biol Psychiatry 2012;73:518–524
DOI: 10.1016/j.biopsych.2012.06.019

Hearing Dysphasic Voices
Hubl et al., Lancet 2007;370:538
DOI: 10.1016/S0140-6736(07)61237-9

Increased connectivity of left fasciculus arcuate in AVH
Hubl et al., Arch Gen Psychiatry 2004;61:658–668
DOI: 10.1001/archpsyc.61.7.658

Episodic activation of left Gyrus Heschl
Dierks et al., Neuron 1999;22:615–621
DOI: 10.1016/S0896-6273(00)80715-1

Formal Thought Disorder
Is formal thought disorder in schizophrenia related to structural and functional aberrations in the language network? A systematic review of neuroimaging findings
Cavelti et al., Schizophr Res 2018;199:2–16
DOI: 10.1016/j.schres.2018.02.051

Decreased blood flow in the right insula and middle temporal gyrus predicts negative formal thought disorder in schizophrenia
Winkelbeiner et al., Schizophr Res 2018;201:432–434
DOI: 10.1016/j.schres.2018.06.009

White matter correlates of the disorganized speech dimension in schizophrenia
Viher et al., Eur Arch Psychiatry Clin Neurosci 2018;12:93–99
DOI: 10.1007/s00406-016-0753-y

Formal thought disorder is related to aberrations in language-related white matter tracts in patients with schizophrenia
Cavelti et al., Psychiatry Res Neuroimaging 2018;279:40–50
DOI: 10.1016/j.pscychresns.2018.05.011

Resting state perfusion in the language network is linked to formal thought disorder and poor functional outcome in schizophrenia
Stegmayer et al., Acta Psychiatrica Scandinavica 2017;136:506–516
DOI: 10.1111/acps.12790

Disintegration of the left semantic network in FTD
Horn et al., Neuropsychobiology 2012;66:14–23
DOI: 10.1159/000337133

Reduced gray matter volume in Wernicke's area in FTD
Horn et al., Psychiatry Res 2010;182:183–186
DOI: 10.1016/j.pscychresns.2010.01.016

Hyperexcitation of the Language System
Horn et al., Br J Psychiatry 2009; 194:130–138
DOI: 10.1192/bjp.bp.107.045633

Language Processing
Anatomical integrity within the inferior fronto-occipital fasciculus and semantic processing deficits in schizophrenia spectrum disorders
Surbeck et al., Schizophr Res 2020;218:267-275
DOI: 10.1016/j.schres.2019.12.025

Blood perfusion in left inferior and middle frontal gyrus predicts communication skills in schizophrenia
Cantisani et al., Psychiatry Res Neuroimaging 2018;274:7-10
DOI: 10.1016/j.pscychresns.2018.02.002