Systems Neuroscience of Psychosis
SyNoPsis
is a research project to investigate structural and functional correlates of sensori-motor brain sytems involved in psychotic behavior and experience.
Research
With current neurobiological empirical knowledge we found evidence for a new description of the schizophrenia symptoms, which is based on the pathophysiology of the brain.
SyNoPsis
proposes a three-dimensional symptom structure, segregated into the
language, affective, and motor domain
Domains
We found that psychotic symptoms can not only be described as categories. They can also be separated into three different symptom dimensions which are related to well-defined brain systems. These dimensions are the language (semantic), affectivity (limbic), and the motor-behavior (executive).
SEMANTIC
Hallucinations, Formal Thought Disorder & the Language System
LIMBIC
Emotions, Delusions & the Limbic System
EXECUTIVE
Motor Function, Non-Verbal Communication & the Motor System
SyNoPsis
is a collaboration of
researchers and clinicians in the
field of psychiatry and neuroscience
Several working groups and collaborators are working in the SyNoPsis framework to improve current diagnostic and therapeutic instruments for people with symptoms of schizophrenia.